And remember
that these “natural” products can interact with your prescription medications or
other supplements in some surprising, even dangerous, ways. Always check with
your doctor or pharmacist for interactions.
Some people
are using supplements of psyllium and other fibers like barley and guar gum for
weight loss. Like some pharmaceuticals, they can prevent fats from being
absorbed.
But instead of
inhibiting enzymatic breakdown of fats as drugs like Orlistat do, these fibers
prevent absorption by binding to fats in the gut. This lets some portion of fats
pass right through the body as harmless passengers on the fiber.
That’s why
increasing fiber intake decreases blood lipid levels. But there is a little
evidence that these fibers alone actually help decrease weight in heavy
patients. Guar gum has been studied the most, but on its own, it does not seem
to be working for weight loss.
The best
weight-loss or weight-control effect to be drawn from fiber comes from simply
consuming more of your daily calories from dietary fiber sources.
If you’re
looking for that fat-blocking function, try eating almonds in moderation.
They’re high in fiber and good monounsaturated fatty acids, and while almonds
are no miracle munchie, recent research shows that the cellular walls in almonds
also have a lipase-blocking property, preventing some absorption of fats in the
gut.
Weight Loss Dietary Supplement - Other
Enticing Promises
Some patients
also ask me about trying dietary supplements that affect serotonin levels in the
brain, in particular, St. John’s wort and 5-HTP. With respect to the appetite
suppressant effects of supplements that act on the serotonin function, St.
John’s wort has a long and solid history as an herbal anti-depressant.
It’s true that
St. John’s wort can inhibit serotonin reuptake, and because of this, it is
prescribed as an anti-depressant in some European countries. But there is no
reliable evidence it helps reduce weight in obese patients, and it doesn’t
consistently produce weight loss in patients who take it for
depression.
A huge number
of other supplements are being tried for obesity. One of the hottest is
conjugated linoleic acid (CLA). CLA refers to isomers of the fatty acid linoleic
acid, which is primarily found in dairy products and beef. Researchers theorize
that CLA might shrink adipose tissue by inducing apoptosis (programmed cell
death) of fat cells.
There’s
preliminary evidence that three to four grams of CLA per day might reduce the
proportional level of body fat mass, but not actual weight or body mass index.
These findings are interesting, and I think it’s too soon to put much store in
them since these supplements are pretty expensive for this minor
effect.
Chromium is
being used to address obesity-related conditions like hyperlipidemia, diabetes,
and obesity. The theory is that American diets are deficient in chromium, which
can lead to diabetes, overweight and other metabolic abnormalities. There is
some evidence that chromium can help reduce lipid and glucose levels in people
with diabetes. But chromium doesn’t seem to help for actual weight
loss.
Garcinia
cambogia fruit and rind extracts contain up to 50 percent hydroxycitric acid,
which manufacturers claim inhibits the body’s production of lipids. This
ingredient appears in tons of supplements promoted for weight loss. But a study
published in the Journal of the American Medical Association shows that it has
no significant effect on weight. Don’t bother.
When it comes
to supplements, consumers need to carefully sort through the marketing blitz. A
few supplements show some promise, but there’s not enough evidence to recommend
them. Especially try to avoid potentially dangerous products that contain
country mallow, or bitter orange that provide ephedrine-like drugs.
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Caroline J. Cederquist, M.D. is a board certified Family Physician and a board certified Bariatric Physicians (the medical specialty of weight management). Dr. Cederquist is the founder of Bistro M.D., a home diet delivery program that specializes in low calorie gourmet food that is delivered to your home or office. Bistro M.D. serves as culmination of Dr. Cederquist's expertise and experience in the world of medical weight loss.